Compliance with QUOROM and quality of reporting of overlapping meta-analyses on the role of acetylcysteine in the prevention of contrast associated nephropathy: case study.

ABSTRACT:

Objective

To appraise multiple systematic reviews on the same clinical topic, focusing on predictors and correlates of quality of reporting of meta-analysis (QUOROM) scores.

Design

Case study.

Setting

Reviews providing at least individual quantitative estimates on role of acetylcysteine in the prevention of contrast associated nephropathy.

Data sources

PubMed, the database of abstracts of reviews of effects, and the Cochrane database of systematic reviews (updated March 2005).

Main outcome measures

Funding, compliance with the QUOROM checklist, scores on the Oxman and Guyatt quality index, and authors' recommendations.

Results

10 systematic reviews, published August 2003 to March 2005, were included. Nine pooled events despite heterogeneity and fi

SUBMITTER: Biondi-Zoccai GG 

PROVIDER: S-EPMC1352049 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature