Circadian analysis of myocardial infarction incidence in an Argentine and Uruguayan population.

ABSTRACT:

Background

The occurrence of variations in the spectrum of cardiovascular disease between different regions of the world and ethnic groups have been the subject of great interest. This study report the 24-h variation of myocardial infarction (MI) occurrence in patients recruited from CCU located in Argentina and Uruguay.

Method

A cohort of 1063 patients admitted to the CCU within 24 h of the onset of symptoms of an acute MI was examined. MI incidence along the day was computed in 1 h-intervals.

Results

A minimal MI incidence between 03:00 and 07:00 h and the occurrence of a first maximum between 08:00 and 12:00 h and a second maximum between 15:00 and 22:00 h were verified. The best fit curve was a 24 h cosinor (acrophase approximately 19:00 h, accounting for 63 % of

SUBMITTER: D'Negri CE 

PROVIDER: S-EPMC1360093 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature