Origin and propagation of epileptic spasms delineated on electrocorticography.

ABSTRACT:

Purpose

Ictal electrographic changes were analyzed on intracranial electrocorticography (ECoG) in children with medically refractory epileptic spasms to assess the dynamic changes of ictal discharges associated with spasms and their relation to interictal epileptiform activity and neuroimaging findings.

Methods

We studied a consecutive series of 15 children (age 0.4 to 13 years; nine girls) with clusters of epileptic spasms recorded on prolonged intracranial subdural ECoG recordings, which were being performed for subsequent cortical resection, and in total, 62 spasms were analyzed by using quantitative methods.

Results

Spasms were associated with either a "leading" spike followed by fast-wave bursts (type I: 42 events analyzed quantitatively) or fast-wave bursts with

SUBMITTER: Asano E 

PROVIDER: S-EPMC1360692 | biostudies-literature | 2005 Jul

REPOSITORIES: biostudies-literature