Prognostic value of the SPICE score for 1-year functional outcomes in patients with acute stroke requiring mechanical ventilation.

ABSTRACT:

Background

Approximately 15 million people suffer from strokes each year and accurate prognostication is crucial for care management. This study evaluated the performance of the Stroke Prognosis in Intensive CarE (SPICE) score to predict functional outcomes at 1 year in patients who underwent mechanical ventilation following a stroke.

Methods

Ancillary analysis of the SPICE prospective multicentre cohort study conducted from 2017 to 2019 in 33 intensive care units (ICUs) of the Greater Paris area. All patients requiring mechanical ventilation on ICU admission and within 7 days of a non-traumatic stroke were included. The primary outcome was poor functional prognosis at 1 year (severe disability or death: modified Rankin Scale score of 4-6). Variables independently associated

SUBMITTER: Mabiala T 

PROVIDER: S-EPMC13630000 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature