Longitudinal Impact of Agitation and Aggression Symptoms on Societal Costs in Alzheimer's Disease: A Focus on Informal Care and Socioeconomic Disparities.

ABSTRACT:

Background

To date, no longitudinal study has assessed the effect of agitation on societal costs-particularly informal care costs-over time in Alzheimer's Disease (AD) patients with Agitation and Aggression (A/A) symptoms.

Objectives

This study estimates the impact of A/A symptoms evolution on longitudinal care costs including informal care costs in moderate-to-severe AD, considering patient and caregiver socioeconomic characteristics.

Design

A longitudinal trajectory clustering method was used on this longitudinal, prospective, multicenter observational cohort study.

Setting and participants

262 community-dwelling and long-term care facility (LTCF) patients of both sexes, aged 60 years and older, with clinically significant A/A symptoms were recruited from mem

SUBMITTER: Costa N 

PROVIDER: S-EPMC13630399 | biostudies-literature | 2026 Oct

REPOSITORIES: biostudies-literature