Bioinformatics analysis of the sodium-dependent neurotransmitter transporter family in Bursaphelenchus xylophilus.

ABSTRACT: Pine wilt disease (PWD), caused by Bursaphelenchus xylophilus, poses a significant threat to global pine forests. The sodium-dependent neurotransmitter transporter (SNF) plays a critical role in the reuptake of neurotransmitters from the synaptic cleft, thereby terminating neural signal transmission and maintaining nervous system homeostasis. This study aimed to comprehensively identify all members of the SNF in B. xylophilus and elucidated their roles in nematode development and nervous system function. Through genome-wide data analysis, we identified 18 SNFs in B. xylophilus and thoroughly characterized their physicochemical properties, conserved motifs, protein structures, and gene expression profiles across different developmental stages. Phylogenetic analysis revealed evolutionary rel

SUBMITTER: He C 

PROVIDER: S-EPMC13640315 | biostudies-literature | 2026 Jul

REPOSITORIES: biostudies-literature