Mapping risk: Spatial analysis of 2,4-D herbicide emissions and colorectal cancer.

ABSTRACT: Colorectal cancer remains a major public health concern in Arkansas and across the United States, disproportionately affecting rural and vulnerable populations. Beyond established lifestyle and genetic factors, environmental exposures, particularly agricultural chemicals, are increasingly recognized as potential contributors. In this ecological study, we screened 133 county-level estimated air pollutants to identify candidates associated with colorectal cancer incidence rates, focusing on Arkansas due to its agricultural economy and widespread herbicide use. Using publicly available environmental and cancer registry data, we applied spatial mapping, correlation tests, linear regression, and spatial regression models. Among screened pollutants, 2,4-Dichlorophenoxyacetic acid (2,4-D), a wide

SUBMITTER: Baxter D 

PROVIDER: S-EPMC13645371 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature