Exploratory Analysis of Type 2 Diabetes Mellitus Metabolic Phenotypes and Their Association With Vitamin D Status in Primary Care Patients.

ABSTRACT:

Aims

This study aimed to perform an exploratory characterisation of metabolic phenotypes in primary care patients with type 2 diabetes mellitus (T2DM), using a predefined approach and examine their association with vitamin D status.

Materials and methods

This cross-sectional study included 178 participants randomly selected in Sergipe, Brazil. Phenotypic clusters were derived using body mass index (BMI), glycated haemoglobin levels, age at diagnosis, insulin resistance (homeostatic model assessment (HOMA) for insulin resistance) and β-cell function (HOMA-B). To explore differences across phenotypes, we evaluated high-sensitivity C-reactive protein [hs-CRP] and serum ferritin levels, waist circumference and BMI, serum concentrations of 25-hydroxyvitamin D [25(OH)D] and therap

SUBMITTER: Pires LV 

PROVIDER: S-EPMC13646376 | biostudies-literature | 2026 Nov

REPOSITORIES: biostudies-literature