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Association of the pan-immune-inflammation value with 60-day in-hospital mortality in critically ill patients with acute myocardial infarction: evidence from the MIMIC-IV database.


ABSTRACT:

Background

Critically ill patients with acute myocardial infarction (AMI) frequently exhibit marked inflammatory and immune dysregulation, which substantially increases their risk of short-term mortality. The pan-immune-inflammation value (PIV) represents an integrated index calculated from neutrophil, monocyte, platelet, and lymphocyte counts. There is currently no systematical evaluation clarifying the link of PIV with 60-day in-hospital mortality in the critically ill patients with AMI. The primary objective of the current study was to assess PIV's prognostic utility and to identify potential threshold effects using data derived from the MIMIC-IV database.

Methods

Three thousand two hundred twenty-four critically ill patients with AMI were included and stratified into ter

SUBMITTER: Wu M 

PROVIDER: S-EPMC13651050 | biostudies-literature | 2026 Jul

REPOSITORIES: biostudies-literature