SOBIR1 integrates pathogen recognition and hormonal metabolism in Nicotiana tabacum.

ABSTRACT: The receptor-like kinase SOBIR1 (SUPPRESSOR OF BIR1) is a core component of immune receptor complexes mediating plant responses to extracellular immunogenic signals. While its role in pattern-triggered immunity is well defined in model species, its broader physiological functions remain largely unexplored. Here, we generated CRISPR-Cas9-derived double knockouts of 2 homeologous SOBIR1 genes in allotetraploid Nicotiana tabacum. The resulting Nt sobir1 double mutants failed to trigger elicitor-induced cell death in response to elicitins from Phytophthora and Pythium spp. but retained an attenuated early reactive oxygen species (ROS) response while lacking sustained ROS accumulation, showing that the transient and sustained ROS outputs differ in their dependence on SOBIR1. Functionally, the m

SUBMITTER: Janotik A 

PROVIDER: S-EPMC13651904 | biostudies-literature | 2026 Oct

REPOSITORIES: biostudies-literature