Human herpesvirus 8 gene encodes a functional thymidylate synthase.

ABSTRACT: We demonstrate that human herpesvirus 8, obtained from the lymphoma cell line BC-3 as well as from Kaposi's sarcoma lesions, carries a gene that encodes a functional thymidylate synthase (TS). The particular characteristics of this enzyme are studied and compared to the characteristics of TSs encoded by other organisms.

SUBMITTER: Gaspar G 

PROVIDER: S-EPMC136588 | biostudies-literature | 2002 Oct

REPOSITORIES: biostudies-literature