Theoretical evaluation of voltage inducement on internal membranes of biological cells exposed to electric fields.

ABSTRACT: Several reports have recently been published on effects of very short and intense electric pulses on cellular organelles; in a number of cases, the cell plasma membrane appeared to be affected less than certain organelle membranes, whereas with longer and less intense pulses the opposite is the case. The effects are the consequence of the voltages induced on the membranes, and in this article we investigate the conditions under which the induced voltage on an organelle membrane could exceed its counterpart on the cell membrane. This would provide a possible explanation of the observed effects of very short pulses. Frequency-domain analysis yields an insight into the dependence of the voltage inducement on the electric and geometric parameters characterizing the cell and its vicinity. We sh

SUBMITTER: Kotnik T 

PROVIDER: S-EPMC1367054 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature