A eukaryotic-type serine/threonine protein kinase is required for biofilm formation, genetic competence, and acid resistance in Streptococcus mutans.

ABSTRACT: We report an operon encoding a eukaryotic-type serine/threonine protein kinase (STPK) and its cognate phosphatase (STPP) in Streptococcus mutans. Mutation of the gene encoding the STPK produced defects in biofilm formation, genetic competence, and acid resistance, determinants important in caries pathogenesis.

SUBMITTER: Hussain H 

PROVIDER: S-EPMC1367251 | biostudies-literature | 2006 Feb

REPOSITORIES: biostudies-literature