Ontology highlight
ABSTRACT:
SUBMITTER: Tassetto M
PROVIDER: S-EPMC1369162 | biostudies-literature | 2005 Sep
REPOSITORIES: biostudies-literature
Tassetto Michel M Maizel Alexis A Osorio Joana J Joliot Alain A
EMBO reports 20050901 9
Homeoproteins are defined by the structure of their DNA-binding domain, the homeodomain. Intercellular transfer of homeoprotein was observed ex vivo between animal cells and in vivo in higher plants. In the latter case, transfer is through intercytoplasmic channels that connect plant cells, but these do not exist in animals. Here, we show that the homeodomain of KNOTTED1, a maize homeoprotein, is transferred between animal cells and that a mutation in the homeodomain blocking the intercellular t ...[more]