Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis.

ABSTRACT:

Objective

To conduct a systematic review of the efficacy and safety of exogenous melatonin in managing secondary sleep disorders and sleep disorders accompanying sleep restriction, such as jet lag and shiftwork disorder.

Data sources

13 electronic databases and reference lists of relevant reviews and included studies; Associated Professional Sleep Society abstracts (1999 to 2003).

Study selection

The efficacy review included randomised controlled trials; the safety review included randomised and non-randomised controlled trials.

Quality assessment

Randomised controlled trials were assessed by using the Jadad Scale and criteria by Schulz et al, and non-randomised controlled trials by the Downs and Black checklist.

Data extraction and synthesis

One reviewe

SUBMITTER: Buscemi N 

PROVIDER: S-EPMC1370968 | biostudies-literature | 2006 Feb

REPOSITORIES: biostudies-literature