Sca1, a previously undescribed paralog from autotransporter protein-encoding genes in Rickettsia species.

ABSTRACT:

Background

Among the 17 genes encoding autotransporter proteins of the "surface cell antigen" (sca) family in the currently sequenced Rickettsia genomes, ompA, sca5 (ompB) and sca4 (gene D), have been extensively used for identification and phylogenetic purposes for Rickettsia species. However, none of these genes is present in all 20 currently validated Rickettsia species. Of the remaining 14 sca genes, sca1 is the only gene to be present in all nine sequenced Rickettsia genomes. To estimate whether the sca1 gene is present in all Rickettsia species and its usefulness as an identification and phylogenetic tool, we searched for sca1genes in the four published Rickettsia genomes and amplified and sequenced this gene in the remaining 16 validated Rickettsia species.

Results

Sc

SUBMITTER: Ngwamidiba M 

PROVIDER: S-EPMC1388218 | biostudies-literature | 2006 Feb

REPOSITORIES: biostudies-literature