Virologic and serologic identification of minute virus of canines (canine parvovirus type 1) from dogs in Japan.

ABSTRACT: Minute virus of canines (MVC), also known as canine parvovirus type 1, was initially believed to be a nonpathogenic agent, since it was first isolated from canine fecal specimens in the late 1960s. However, subsequent pathological as well as epidemiological studies suggested that MVC is a pathogen of neonatal puppies and is widely distributed among domestic dogs in the United States. The virus also has been shown to cause fetal deaths. Nevertheless, the virus was not detected in dogs outside the United States until recently, presumably because of a lack of widespread availability of the only susceptible canine cell line, WRCC/3873D, used for MVC isolation. We examined 470 clinical specimens from 346 dogs by PCR and detected MVC-specific gene fragments from four diseased puppies (positive r

SUBMITTER: Mochizuki M 

PROVIDER: S-EPMC139639 | biostudies-literature | 2002 Nov

REPOSITORIES: biostudies-literature