Many genes in fish have species-specific asymmetric rates of molecular evolution.

ABSTRACT:

Background

Gene and genome duplication events increase the amount of genetic material that might then contribute to an increase in the genomic and phenotypic complexity of organisms during evolution. Thus, it has been argued that there is a relationship between gene copy number and morphological complexity and/or species diversity. This hypothesis implies that duplicated genes have subdivided or evolved novel functions compared to their pre-duplication proto-orthologs. Such a functional divergence might be caused by an increase in evolutionary rates in one ortholog, by changes in expression, regulatory evolution, insertion of repetitive elements, or due to positive Darwinian selection in one copy. We studied a set of 2466 genes that were present in Danio rerio, Takifugu rubripes, T

SUBMITTER: Steinke D 

PROVIDER: S-EPMC1413527 | biostudies-literature | 2006 Feb

REPOSITORIES: biostudies-literature