High resolution physical map of porcine chromosome 7 QTL region and comparative mapping of this region among vertebrate genomes.

ABSTRACT:

Background

On porcine chromosome 7, the region surrounding the Major Histocompatibility Complex (MHC) contains several Quantitative Trait Loci (QTL) influencing many traits including growth, back fat thickness and carcass composition. Previous studies highlighted that a fragment of approximately 3.7 Mb is located within the Swine Leucocyte Antigen (SLA) complex. Internal rearrangements of this fragment were suggested, and partial contigs had been built, but further characterization of this region and identification of all human chromosomal fragments orthologous to this porcine fragment had to be carried out.

Results

A whole physical map of the region was constructed by integrating Radiation Hybrid (RH) mapping, BAC fingerprinting data of the INRA BAC library and anchoring BA

SUBMITTER: Demars J 

PROVIDER: S-EPMC1420295 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature