Refined localization of the FAT1 quantitative trait locus on pig chromosome 4 by marker-assisted backcrossing.

ABSTRACT:

Background

A major QTL for fatness and growth, denoted FAT1, has previously been detected on pig chromosome 4q (SSC4q) using a Large White - wild boar intercross. Progeny that carried the wild boar allele at this locus had higher fat deposition, shorter length of carcass, and reduced growth. The position and the estimated effects of the FAT1 QTL for growth and fatness have been confirmed in a previous study. In order to narrow down the QTL interval we have traced the inheritance of the wild boar allele associated with high fat deposition through six additional backcross generations.

Results

Progeny-testing was used to determine the QTL genotype for 10 backcross sires being heterozygous for different parts of the broad FAT1 region. The statistical analysis revealed that five

SUBMITTER: Berg F 

PROVIDER: S-EPMC1431559 | biostudies-literature | 2006 Mar

REPOSITORIES: biostudies-literature