Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2.

ABSTRACT:

Background

Streptococcus suis serotype 2 (S. suis 2, SS2) is a major zoonotic pathogen that causes only sporadic cases of meningitis and sepsis in humans. Most if not all cases of Streptococcal toxic shock syndrome (STSS) that have been well-documented to date were associated with the non-SS2 group A streptococcus (GAS). However, a recent large-scale outbreak of SS2 in Sichuan Province, China, appeared to be caused by more invasive deep-tissue infection with STSS, characterized by acute high fever, vascular collapse, hypotension, shock, and multiple organ failure.

Methods and findings

We investigated this outbreak of SS2 infections in both human and pigs, which took place from July to August, 2005, through clinical observation and laboratory experiments. Clinical and patholo

SUBMITTER: Tang J 

PROVIDER: S-EPMC1434494 | biostudies-literature | 2006 May

REPOSITORIES: biostudies-literature