Development of a chicken 5 K microarray targeted towards immune function.

ABSTRACT:

Background

The development of microarray resources for the chicken is an important step in being able to profile gene expression changes occurring in birds in response to different challenges and stimuli. The creation of an immune-related array is highly valuable in determining the host immune response in relation to infection with a wide variety of bacterial and viral diseases.

Results

Here we report the development of chicken immune-related cDNA libraries and the subsequent construction of a microarray containing 5190 elements (in duplicate). Clones on the array originate from tissues known to contain high levels of cells related to the immune system, namely Bursa, Peyers patch, thymus and spleen. Represented on the array are genes that are known to cluster with existing c

SUBMITTER: Smith J 

PROVIDER: S-EPMC1440325 | biostudies-literature | 2006 Mar

REPOSITORIES: biostudies-literature