The time-profile of cell growth in fission yeast: model selection criteria favoring bilinear models over exponential ones.

ABSTRACT:

Background

There is considerable controversy concerning the exact growth profile of size parameters during the cell cycle. Linear, exponential and bilinear models are commonly considered, and the same model may not apply for all species. Selection of the most adequate model to describe a given data-set requires the use of quantitative model selection criteria, such as the partial (sequential) F-test, the Akaike information criterion and the Schwarz Bayesian information criterion, which are suitable for comparing differently parameterized models in terms of the quality and robustness of the fit but have not yet been used in cell growth-profile studies.

Results

Length increase data from representative individual fission yeast (Schizosaccharomyces pombe) cells measured on time-

SUBMITTER: Buchwald P 

PROVIDER: S-EPMC1444923 | biostudies-literature | 2006 Mar

REPOSITORIES: biostudies-literature