A method for similarity search of genomic positional expression using CAGE.

ABSTRACT: With the advancement of genome research, it is becoming clear that genes are not distributed on the genome in random order. Clusters of genes distributed at localized genome positions have been reported in several eukaryotes. Various correlations have been observed between the expressions of genes in adjacent or nearby positions along the chromosomes depending on tissue type and developmental stage. Moreover, in several cases, their transcripts, which control epigenetic transcription via processes such as transcriptional interference and genomic imprinting, occur in clusters. It is reasonable that genomic regions that have similar mechanisms show similar expression patterns and that the characteristics of expression in the same genomic regions differ depending on tissue type and developmen

SUBMITTER: Seno S 

PROVIDER: S-EPMC1449887 | biostudies-literature | 2006 Apr

REPOSITORIES: biostudies-literature