Using green fluorescent malaria parasites to screen for permissive vector mosquitoes.

ABSTRACT:

Background

The Plasmodium species that infect rodents, particularly Plasmodium berghei and Plasmodium yoelii, are useful to investigate host-parasite interactions. The mosquito species that act as vectors of human plasmodia in South East Asia, Africa and South America show different susceptibilities to infection by rodent Plasmodium species. P. berghei and P. yoelii infect both Anopheles gambiae and Anopheles stephensi, which are found mainly in Africa and Asia, respectively. However, it was reported that P. yoelii can infect the South American mosquito, Anopheles albimanus, while P. berghei cannot.

Methods

P. berghei lines that express the green fluorescent protein were used to screen for mosquitoes that are susceptible to infection by P. berghei. Live mosquitoes were exami

SUBMITTER: Frischknecht F 

PROVIDER: S-EPMC1450296 | biostudies-literature | 2006 Mar

REPOSITORIES: biostudies-literature