A cis-regulatory sequence within the yellow locus of Drosophila melanogaster required for normal male mating success.

ABSTRACT: Drosophila melanogaster males perform a courtship ritual consisting of a series of dependent fixed-action patterns. The yellow (y) gene is required for normal male courtship behavior and subsequent mating success. To better characterize the requirement for y in the manifestation of innate male sexual behavior, we measured the male mating success (MMS) of 12 hypomorphic y mutants and matched-outbred-background controls using a y+ rescue element on a freely segregating minichromosome. We found that 4 hypomorphs significantly reduced MMS to varying degrees. Reduced MMS was largely independent of adult pigmentation patterns. These mutations defined a 300-bp regulatory region upstream of the transcription start, the mating-success regulatory sequence (MRS), whose function is required for normal

SUBMITTER: Drapeau MD 

PROVIDER: S-EPMC1456202 | biostudies-literature | 2006 Feb

REPOSITORIES: biostudies-literature