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Discrepancies between recombination frequencies and physical distances in Aspergillus nidulans: implications for gene identification.


ABSTRACT: A rapid route to gene molecular identification involves using recombination frequencies in locating mutational sequence changes. We describe a case where the recombination frequency is deceptively low, probably reflecting centromere proximity. Recombination frequencies are greatly reduced near the centromeres on the right arms of chromosomes III and IV of Aspergillus nidulans.

SUBMITTER: Espeso EA 

PROVIDER: S-EPMC1456791 | biostudies-literature | 2005 Oct

REPOSITORIES: biostudies-literature

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Discrepancies between recombination frequencies and physical distances in Aspergillus nidulans: implications for gene identification.

Espeso Eduardo A EA   Cobeño Laura L   Arst Herbert N HN  

Genetics 20050714 2


A rapid route to gene molecular identification involves using recombination frequencies in locating mutational sequence changes. We describe a case where the recombination frequency is deceptively low, probably reflecting centromere proximity. Recombination frequencies are greatly reduced near the centromeres on the right arms of chromosomes III and IV of Aspergillus nidulans. ...[more]

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