SCOWLP: a web-based database for detailed characterization and visualization of protein interfaces.

ABSTRACT:

Background

Currently there is a strong need for methods that help to obtain an accurate description of protein interfaces in order to be able to understand the principles that govern molecular recognition and protein function. Many of the recent efforts to computationally identify and characterize protein networks extract protein interaction information at atomic resolution from the PDB. However, they pay none or little attention to small protein ligands and solvent. They are key components and mediators of protein interactions and fundamental for a complete description of protein interfaces. Interactome profiling requires the development of computational tools to extract and analyze protein-protein, protein-ligand and detailed solvent interaction information from the PDB in an aut

SUBMITTER: Teyra J 

PROVIDER: S-EPMC1459204 | biostudies-literature | 2006 Mar

REPOSITORIES: biostudies-literature