Cerebral emboli as a potential cause of Alzheimer's disease and vascular dementia: case-control study.

ABSTRACT:

Objective

To compare the occurrence of spontaneous cerebral emboli and venous to arterial circulation shunts in patients with Alzheimer's disease or vascular dementia and controls without dementia.

Design

Cross sectional case-control study.

Setting

Secondary care old age psychiatry services, Manchester.

Participants

170 patients with dementia (85 with Alzheimer's disease, 85 with vascular dementia) and 150 age and sex matched controls. Patients on anticoagulant treatment, patients with severe dementia, and controls with marked cognitive impairment were excluded.

Main outcome measures

Frequencies of detection of spontaneous cerebral emboli during one hour monitoring of the middle cerebral arteries with transcranial Doppler and venous to arterial circulati

SUBMITTER: Purandare N 

PROVIDER: S-EPMC1459546 | biostudies-literature | 2006 May

REPOSITORIES: biostudies-literature