Natural variation in a subtelomeric region of Arabidopsis: implications for the genomic dynamics of a chromosome end.

ABSTRACT: We investigated genome dynamics at a chromosome end in the model plant Arabidopsis thaliana through a study of natural variation in 35 wild accessions. We focused on the single-copy subtelomeric region of chromosome 1 north (approximately 3.5 kb), which represents the relatively simple organization of subtelomeric regions in this species. PCR fragment-length variation across the subtelomeric region indicated that the 1.4-kb distal region showed elevated structural variation relative to the centromere-proximal region. Examination of nucleotide sequences from this 1.4-kb region revealed diverse DNA rearrangements, including an inversion, several deletions, and an insertion of a retrotransposon LTR. The structures at the deletion and inversion breakpoints are characteristic of simple deletion

SUBMITTER: Kuo HF 

PROVIDER: S-EPMC1461430 | biostudies-literature | 2006 May

REPOSITORIES: biostudies-literature