High-risk human papilloma virus (HPV) and survival in patients with esophageal carcinoma: a pilot study.

ABSTRACT:

Background

Human papilloma virus (HPV) in patients with esophageal carcinoma has previously been studied with an average detection rate of 15%, but the role of HPV in relation to survival is less clear. In cervical cancer, lung cancer and tonsil cancer HPV viral load is a predictive factor for survival and outcome of treatment. The primary aim was to study the spectrum of high-risk HPV types in esophageal tumors. Secondary, as a pilot study we investigated the association between HPV status and the survival rates.

Methods

We compared both the presence and the viral load of high-risk HPV types 16, 18, 31, 33, 39, 45, 52, 58, and 67 in relation to clinical data from patients with esophageal carcinoma. Survival data and tumor samples were retrieved from 100 patients receiving t

SUBMITTER: Dreilich M 

PROVIDER: S-EPMC1475606 | biostudies-literature | 2006 Apr

REPOSITORIES: biostudies-literature