Genomic analysis of carbon source metabolism of Shewanella oneidensis MR-1: Predictions versus experiments.

ABSTRACT: Genomic sequences have been used to find the genetic foundation for carbon source metabolism in Shewanella oneidensis MR-1. Annotated S. oneidensis MR-1 gene products were examined for their sequence similarity to enzymes participating in pathways for utilization of carbon and energy as described in the BioCyc database (http://www.biocyc.org/) or in the primary literature. A picture emerges that relegates five- and six-carbon sugars to minor roles as carbon sources, whereas multiple pathways for utilization of up to three-carbon carbohydrates seem to be present. Capacity to utilize amino acids for carbon and energy is also present. A few contradictions emerged in which enzymes appear to be present by annotations but are not active in the cell according to physiological experiments. Annotat

SUBMITTER: Serres MH 

PROVIDER: S-EPMC1482980 | biostudies-literature | 2006 Jul

REPOSITORIES: biostudies-literature