Evolution of four gene families with patchy phylogenetic distributions: influx of genes into protist genomes.

ABSTRACT:

Background

Lateral gene transfer (LGT) in eukaryotes from non-organellar sources is a controversial subject in need of further study. Here we present gene distribution and phylogenetic analyses of the genes encoding the hybrid-cluster protein, A-type flavoprotein, glucosamine-6-phosphate isomerase, and alcohol dehydrogenase E. These four genes have a limited distribution among sequenced prokaryotic and eukaryotic genomes and were previously implicated in gene transfer events affecting eukaryotes. If our previous contention that these genes were introduced by LGT independently into the diplomonad and Entamoeba lineages were true, we expect that the number of putative transfers and the phylogenetic signal supporting LGT should be stable or increase, rather than decrease, when novel e

SUBMITTER: Andersson JO 

PROVIDER: S-EPMC1484493 | biostudies-literature | 2006 Mar

REPOSITORIES: biostudies-literature