Secondary outcomes of a pilot randomized trial of azithromycin treatment for asthma.

ABSTRACT:

Objectives

The respiratory pathogen Chlamydia pneumoniae (C. pneumoniae) produces acute and chronic lung infections and is associated with asthma. Evidence for effectiveness of antichlamydial antibiotics in asthma is limited. The primary objective of this pilot study was to investigate the feasibility of performing an asthma clinical trial in practice settings where most asthma is encountered and managed. The secondary objectives were to investigate (1) whether azithromycin treatment would affect any asthma outcomes and (2) whether C. pneumoniae serology would be related to outcomes. This report presents the secondary results.

Design

Randomized, placebo-controlled, blinded (participants, physicians, study personnel, data analysts), allocation-concealed parallel group clinica

SUBMITTER: Hahn DL 

PROVIDER: S-EPMC1488900 | biostudies-literature | 2006 Jun

REPOSITORIES: biostudies-literature