Outer membrane protein genes and their small non-coding RNA regulator genes in Photorhabdus luminescens.

ABSTRACT:

Introduction

Three major outer membrane protein genes of Escherichia coli, ompF, ompC, and ompA respond to stress factors. Transcripts from these genes are regulated by the small non-coding RNAs micF, micC, and micA, respectively. Here we examine Photorhabdus luminescens, an organism that has a different habitat from E. coli for outer membrane protein genes and their regulatory RNA genes.

Results

By bioinformatics analysis of conserved genetic loci, mRNA 5'UTR sequences, RNA secondary structure motifs, upstream promoter regions and protein sequence homologies, an ompF -like porin gene in P. luminescens as well as a duplication of this gene have been predicted. Gene loci for micF RNA, as well as OmpC protein and its associated regulatory micC RNA, were not found. Significantl

SUBMITTER: Papamichail D 

PROVIDER: S-EPMC1489923 | biostudies-literature | 2006 May

REPOSITORIES: biostudies-literature