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Nonconjugative transposition of the vanB-containing Tn5382-like element in Enterococcus faecium.

ABSTRACT: The vanB2 operon encoding glycopeptide resistance is an integral part of the putative conjugative transposon Tn5382. Characterization of clinical glycopeptide resistant derivatives from an epidemic ampicillin-resistant Enterococcus faecium strain showed precise chromosomal or plasmid insertions of a vanB2-containing Tn5382-like element. Conjugative transposition of the Tn5382-like element was not demonstrated in retransfer studies.

SUBMITTER: Dahl KH 

PROVIDER: S-EPMC151725 | biostudies-literature | 2003 Feb

REPOSITORIES: biostudies-literature

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Nonconjugative transposition of the vanB-containing Tn5382-like element in Enterococcus faecium.

Dahl Kristin H KH   Røkenes Torunn P TP   Lundblad Eirik W EW   Sundsfjord Arnfinn A  

Antimicrobial agents and chemotherapy 20030201 2

The vanB2 operon encoding glycopeptide resistance is an integral part of the putative conjugative transposon Tn5382. Characterization of clinical glycopeptide resistant derivatives from an epidemic ampicillin-resistant Enterococcus faecium strain showed precise chromosomal or plasmid insertions of a vanB2-containing Tn5382-like element. Conjugative transposition of the Tn5382-like element was not demonstrated in retransfer studies. ...[more]

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