Factors affecting left ventricular remodeling after valve replacement for aortic stenosis. An overview.

ABSTRACT: Although a small percentage of patients with critical aortic stenosis do not develop left ventricle hypertrophy, increased ventricular mass is widely observed in conditions of increased afterload. There is growing epidemiological evidence that hypertrophy is associated with excess cardiac mortality and morbidity not only in patients with arterial hypertension, but also in those undergoing aortic valve replacement. Valve replacement surgery relieves the aortic obstruction and prolongs the life of many patients, but favorable or adverse left ventricular remodeling is affected by a large number of factors whose specific roles are still a subject of debate. Age, gender, hemodynamic factors, prosthetic valve types, myocyte alterations, interstitial structures, blood pressure control and ethnici

SUBMITTER: Villa E 

PROVIDER: S-EPMC1524988 | biostudies-literature | 2006 Jun

REPOSITORIES: biostudies-literature