Bacterial repetitive extragenic palindromic sequences are DNA targets for Insertion Sequence elements.

ABSTRACT:

Background

Mobile elements are involved in genomic rearrangements and virulence acquisition, and hence, are important elements in bacterial genome evolution. The insertion of some specific Insertion Sequences had been associated with repetitive extragenic palindromic (REP) elements. Considering that there are a sufficient number of available genomes with described REPs, and exploiting the advantage of the traceability of transposition events in genomes, we decided to exhaustively analyze the relationship between REP sequences and mobile elements.

Results

This global multigenome study highlights the importance of repetitive extragenic palindromic elements as target sequences for transposases. The study is based on the analysis of the DNA regions surrounding the 981 instances

SUBMITTER: Tobes R 

PROVIDER: S-EPMC1525189 | biostudies-literature | 2006 Mar

REPOSITORIES: biostudies-literature