Prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease: systematic review.

ABSTRACT:

Objectives

To ascertain the prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease and its association with the disease.

Design

Systematic review of studies reporting the prevalence of H pylori in patients with and without gastro-oesophageal reflux disease.

Data sources

Four electronic databases, searched to November 2001, experts, pharmaceutical companies, and journals.

Main outcome measure

Odds ratio for prevalence of H pylori in patients with gastro-oesophageal reflux disease.

Results

20 studies were included. The pooled estimate of the odds ratio for prevalence of H pylori was 0.60 (95% confidence interval 0.47 to 0.78), indicating a lower prevalence in patients with gastro-oesophageal reflux disease. Substantial heterog

SUBMITTER: Raghunath A 

PROVIDER: S-EPMC152634 | biostudies-literature | 2003 Apr

REPOSITORIES: biostudies-literature