Divergence with gene flow in Anopheles funestus from the Sudan Savanna of Burkina Faso, West Africa.

ABSTRACT: Anopheles funestus is a major vector of malaria across Africa. Understanding its complex and nonequilibrium population genetic structure is an important challenge that must be overcome before vector populations can be successfully perturbed for malaria control. Here we examine the role of chromosomal inversions in structuring genetic variation and facilitating divergence in Burkina Faso, West Africa, where two incipient species (chromosomal forms) of A. funestus, defined principally by rearrangements of chromosome 3R, have been hypothesized. Sampling across an approximately 300-km east-west transect largely contained within the Sudan-Savanna ecoclimatic zone, we analyzed chromosomal inversions, 16 microsatellite loci distributed genomewide, and 834 bp of the mtDNA ND5 gene. Both molecular

SUBMITTER: Michel AP 

PROVIDER: S-EPMC1526678 | biostudies-literature | 2006 Jul

REPOSITORIES: biostudies-literature