A revised annotation and comparative analysis of Helicobacter pylori genomes.

ABSTRACT: Huge amounts of genomic information are currently being generated. Therefore, biologists require structured, exhaustive and comparative databases. The PyloriGene database (http://genolist.pasteur.fr/PyloriGene) was developed to respond to these needs, by integrating and connecting the information generated during the sequencing of two distinct strains of Helicobacter pylori. This led to the need for a general annotation consensus, as the physical and functional annotations of the two strains differed significantly in some cases. A revised functional classification system was created to accommodate the existing data and to make it possible to classify coding sequences (CDS) into several functional categories to harmonize CDS classification. The annotation of the two complete genomes was rev

SUBMITTER: Boneca IG 

PROVIDER: S-EPMC152854 | biostudies-literature | 2003 Mar

REPOSITORIES: biostudies-literature