New integron-associated gene cassette encoding a trimethoprim-resistant DfrB-type dihydrofolate reductase.

ABSTRACT: A sixth gene cassette containing a dfrB-type gene, dfrB6, was found in a dfrB6-aadA1 cassette array in class 1 integrons. This array was isolated from several multiply antibiotic-resistant Salmonella enterica serovar Infantis strains that appear to be clonally related. The DfrB6 dihydrofolate reductase conferred resistance to trimethoprim.

SUBMITTER: Levings RS 

PROVIDER: S-EPMC1538648 | biostudies-literature | 2006 Aug

REPOSITORIES: biostudies-literature