FeatureMap3D--a tool to map protein features and sequence conservation onto homologous structures in the PDB.

ABSTRACT: FeatureMap3D is a web-based tool that maps protein features onto 3D structures. The user provides sequences annotated with any feature of interest, such as post-translational modifications, protease cleavage sites or exonic structure and FeatureMap3D will then search the Protein Data Bank (PDB) for structures of homologous proteins. The results are displayed both as an annotated sequence alignment, where the user-provided annotations as well as the sequence conservation between the query and the target sequence are displayed, and also as a publication-quality image of the 3D protein structure with the selected features and sequence conservation enhanced. The results are also returned in a readily parsable text format as well as a PyMol (http://pymol.sourceforge.net/) script file, which all

SUBMITTER: Wernersson R 

PROVIDER: S-EPMC1538770 | biostudies-literature | 2006 Jul

REPOSITORIES: biostudies-literature