MeMo: a web tool for prediction of protein methylation modifications.

ABSTRACT: Protein methylation is an important and reversible post-translational modification of proteins (PTMs), which governs cellular dynamics and plasticity. Experimental identification of the methylation site is labor-intensive and often limited by the availability of reagents, such as methyl-specific antibodies and optimization of enzymatic reaction. Computational analysis may facilitate the identification of potential methylation sites with ease and provide insight for further experimentation. Here we present a novel protein methylation prediction web server named MeMo, protein methylation modification prediction, implemented in Support Vector Machines (SVMs). Our present analysis is primarily focused on methylation on lysine and arginine, two major protein methylation sites. However, our comp

SUBMITTER: Chen H 

PROVIDER: S-EPMC1538891 | biostudies-literature | 2006 Jul

REPOSITORIES: biostudies-literature