Clonal dissemination of Yersinia enterocolitica strains with various susceptibilities to nalidixic acid.

ABSTRACT: Ten epidemiologically related Yersinia enterocolitica clinical isolates were studied. Six isolates were nalidixic acid resistant (MIC > 512 microg/ml), with mutations in the quinolone resistance-determining region (QRDR) of the gyrA gene, suggesting clonal dissemination of a nalidixic acid-susceptible Y. enterocolitica strain which has acquired different mutations generating resistance to nalidixic acid.

SUBMITTER: Sanchez-Cespedes J 

PROVIDER: S-EPMC153901 | biostudies-literature | 2003 Apr

REPOSITORIES: biostudies-literature