Genomic structure and expression of uncoupling protein 2 genes in rainbow trout (Oncorhynchus mykiss).

ABSTRACT:

Background

Uncoupling protein 2 (UCP2) belongs to the superfamily of mitochondrial anion carriers that dissociate the respiratory chain from ATP synthesis. It has been determined that UCP2 plays a role in several physiological processes such as energy expenditure, body weight control and fatty acid metabolism in several vertebrate species. We report the first characterization of UCP2s in rainbow trout (Oncorhynchus mykiss).

Results

Two UCP2 genes were identified in the rainbow trout genome, UCP2A and UCP2B. These genes are 93% similar in their predicted amino acid sequences and display the same genomic structure as other vertebrates (8 exons and 7 introns) spanning 4.2 kb and 3.2 kb, respectively. UCP2A and UCP2B were widely expressed in all tissues of the study with a predo

SUBMITTER: Coulibaly I 

PROVIDER: S-EPMC1559616 | biostudies-literature | 2006 Aug

REPOSITORIES: biostudies-literature