Gene order data from a model amphibian (Ambystoma): new perspectives on vertebrate genome structure and evolution.

ABSTRACT:

Background

Because amphibians arise from a branch of the vertebrate evolutionary tree that is juxtaposed between fishes and amniotes, they provide important comparative perspective for reconstructing character changes that have occurred during vertebrate evolution. Here, we report the first comparative study of vertebrate genome structure that includes a representative amphibian. We used 491 transcribed sequences from a salamander (Ambystoma) genetic map and whole genome assemblies for human, mouse, rat, dog, chicken, zebrafish, and the freshwater pufferfish Tetraodon nigroviridis to compare gene orders and rearrangement rates.

Results

Ambystoma has experienced a rate of genome rearrangement that is substantially lower than mammalian species but similar to that of chicken an

SUBMITTER: Smith JJ 

PROVIDER: S-EPMC1560138 | biostudies-literature | 2006 Aug

REPOSITORIES: biostudies-literature