Predicting essential components of signal transduction networks: a dynamic model of guard cell abscisic acid signaling.

ABSTRACT: Plants both lose water and take in carbon dioxide through microscopic stomatal pores, each of which is regulated by a surrounding pair of guard cells. During drought, the plant hormone abscisic acid (ABA) inhibits stomatal opening and promotes stomatal closure, thereby promoting water conservation. Dozens of cellular components have been identified to function in ABA regulation of guard cell volume and thus of stomatal aperture, but a dynamic description is still not available for this complex process. Here we synthesize experimental results into a consistent guard cell signal transduction network for ABA-induced stomatal closure, and develop a dynamic model of this process. Our model captures the regulation of more than 40 identified network components, and accords well with previous expe

SUBMITTER: Li S 

PROVIDER: S-EPMC1564158 | biostudies-literature | 2006 Oct

REPOSITORIES: biostudies-literature