Quantitative genomics of aggressive behavior in Drosophila melanogaster.

ABSTRACT: Aggressive behavior is important for animal survival and reproduction, and excessive aggression is an enormous social and economic burden for human society. Although the role of biogenic amines in modulating aggressive behavior is well characterized, other genetic mechanisms affecting this complex behavior remain elusive. Here, we developed an assay to rapidly quantify aggressive behavior in Drosophila melanogaster, and generated replicate selection lines with divergent levels of aggression. The realized heritability of aggressive behavior was approximately 0.10, and the phenotypic response to selection specifically affected aggression. We used whole-genome expression analysis to identify 1,539 probe sets with different expression levels between the selection lines when pooled across repli

SUBMITTER: Edwards AC 

PROVIDER: S-EPMC1564424 | biostudies-literature | 2006 Sep

REPOSITORIES: biostudies-literature