The exon context and distribution of Euascomycetes rRNA spliceosomal introns.

ABSTRACT: BACKGROUND:We have studied spliceosomal introns in the ribosomal (r)RNA of fungi to discover the forces that guide their insertion and fixation. RESULTS:Comparative analyses of flanking sequences at 49 different spliceosomal intron sites showed that the G - intron - G motif is the conserved flanking sequence at sites of intron insertion. Information analysis showed that these rRNA introns contain significant information in the flanking exons. Analysis of all rDNA introns in the three phylogenetic domains and two organelles showed that group I introns are usually located after the most conserved sites in rRNA, whereas spliceosomal introns occur at less conserved positions. The distribution of spliceosomal and group I introns in the primary structure of small and large subunit rRNAs was test

SUBMITTER: Bhattacharya D 

PROVIDER: S-EPMC156610 | biostudies-literature | 2003 Apr

REPOSITORIES: biostudies-literature